Hi,
Galaxy Watch Studio 2.0.1 is compatible with macOS Monterey. It has some issues with generating an AOD (it doesn’t remember it when you reload a project and you get a missing resource error when you build.)
For GWS 2.0.0 see this thread Galaxy Watch Studio and Mac Big Sur Update - #118 by agepictures
By the Way once you have it installed you will need to contact developer support and request they send you a Mac version of SDB as the one that comes with GWS does not work. You can also download Tizen Studio and get the SDB from that.
Hope this helps.
Ron
Samsung Developer Relations